Norgestrienone

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Norgestrienone
Norgestrienone.svg
Systematic (IUPAC) name
17-Hydroxy-19-norpregna-4,9,11-trien-20-yn-3-one
Identifiers
CAS Number 848-21-5 N
ATC code G03AC07 (WHO)
PubChem CID 13313
ChemSpider 12749 YesY
UNII 89386PYU9O YesY
KEGG D07220 YesY
Chemical data
Formula C20H22O2
Molar mass 294.387 g/mol
 NYesY (what is this?)  (verify)

Norgestrienone (INN) (brand name Ogyline, Planor), also known as 10,11-didehydro-orethisterone,[1] as well as 17α-ethynyltrienolone (17α-ethynyltrenbolone), is a steroidal progestin that is used as a hormonal contraceptive, sometimes in combination with ethinyl estradiol.[2][3][4] It is a relatively weak progestin, and has some androgenic effects.[5] Norgestrienone was first described in the 1965.[6] Gestrinone is the ethyl derivative of norgestrienone.[7]

References[edit]

  1. ^ J.P. Lavery; J.S. Sanfilippo (6 December 2012). Pediatric and Adolescent Obstetrics and Gynecology. Springer Science & Business Media. pp. 236–. ISBN 978-1-4612-5064-7. 
  2. ^ J. Elks (14 November 2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. pp. 887–. ISBN 978-1-4757-2085-3. 
  3. ^ I.K. Morton; Judith M. Hall (6 December 2012). Concise Dictionary of Pharmacological Agents: Properties and Synonyms. Springer Science & Business Media. pp. 202–. ISBN 978-94-011-4439-1. 
  4. ^ Diaz, S.; Pavez, M.; Quinteros, E.; Diaz, J.; Robertson, D. N.; Croxatto, H. B. (1978). "Clinical trial with subdermal implants containing norgestrienone". Contraception. 18 (4): 429–440. doi:10.1016/0010-7824(78)90027-6. PMID 720075. 
  5. ^ Julius Axelrod (1 January 1982). Biochemical Actions of Hormones. Academic Press. ISBN 978-0-12-452809-3. 
  6. ^ Christian Lauritzen; John W. W. Studd (22 June 2005). Current Management of the Menopause. CRC Press. pp. 45–. ISBN 978-0-203-48612-2. 
  7. ^ Victor Gomel; Andrew Brill (27 September 2010). Reconstructive and Reproductive Surgery in Gynecology. CRC Press. pp. 90–. ISBN 978-1-84184-757-3.