Normal anion gap acidosis

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Normal anion gap acidosis
Classification and external resources
Specialty endocrinology
ICD-10 E87.2
ICD-9-CM 276.2
DiseasesDB 29144

In renal physiology, normal anion gap acidosis, and less precisely non-anion gap acidosis, is an acidosis that is not accompanied by an abnormally increased anion gap.

The most common cause of normal anion gap acidosis is diarrhea with a renal tubular acidosis being a distant second.

Differential diagnosis[edit]

The differential diagnosis of normal anion gap acidosis is relatively short (when compared to the differential diagnosis of acidosis):

As opposed to high anion gap acidosis (which involves increased organic acid production), normal anion gap acidosis involves either increased production of chloride (hyperchloremic acidosis) or increased excretion of bicarbonate.

See also[edit]


  1. ^ "Metabolic Acidosis: Acid-Base Regulation and Disorders: Merck Manual Professional". Retrieved 2008-12-04. 
  2. ^ Jean-Louis Vincent; Abraham Edward; Kochanek Patrick (8 July 2011). "Acid-base disorders". Textbook of Critical Care. Elsevier. ISBN 143771367X.