Trisyngyne nuda

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Trisyngyne nuda
Scientific classification
Kingdom: Plantae
(unranked): Angiosperms
(unranked): Eudicots
(unranked): Rosids
Order: Fagales
Family: Nothofagaceae
Genus: Trisyngyne
Species: T. nuda
Binomial name
Trisyngyne nuda
(Steenis) Heenan & Smissen
Synonyms

Nothofagus nuda

Trisyngyne nuda is a species of plant in the Nothofagaceae family. It is endemic to Papua New Guinea. It is threatened by habitat loss. T. nuda was known as Nothofagus nuda prior to 2013.[1]

In 1927, T. nuda was reported by J. R. Croft to account for 949 deaths throughout Papua New Guinea.[2] The plant is traditionally used as an herb in culinary dishes throughout the Puri Puri[disambiguation needed] tribes of the Papua New Guinea highlands but results in hypoglycemic shock after ingestion of large doses.[3] Croft reported that wives within the polygamous tribes of the Puri Puri used the herb to poison the patriarchs during tribal disputes that coincided with the winter solstice.[4]

Scientists in Macao Laboratory isolated the active molecule of the plant in late 2006.[5] The molecule was determined to be an IRS-1 adaptor molecule involved the insulin response cascade.[6][7][8]

References[edit]

  1. ^ HEENAN, PETER B.; SMISSEN, ROB D. (2013). "Revised circumscription of Nothofagus and recognition of the segregate genera Fuscospora, Lophozonia, and Trisyngyne (Nothofagaceae)". Phytotaxa. 146 (1): 131. doi:10.11646/phytotaxa.146.1.1. Retrieved 31 May 2015. 
  2. ^ http://www.pngplants.org/References/HandbooksPNG_1.pdf
  3. ^ ASIN 0792274172
  4. ^ http://www.papuaweb.org/dlib/bk/french/03.pdf
  5. ^ http://www.gplmacao.com/index_en.asp
  6. ^ Phanstiel O; Zhou, B; Breitbeil, F; Hardy, K; Kraft, KS; Trantcheva, I; Phanstiel O, 4th (2008), "A delineation of diketopiperazine self-assembly processes: understanding the molecular events involved in Nepsilon-(fumaroyl)diketopiperazine of L-Lys (FDKP) interactions", Mol Pharm, 5 (2): 294–315, PMID 18254597, doi:10.1021/mp700096e 
  7. ^ Lambert S; Lambert, S (1999), "Physiological roles of axonal ankyrins in survival of premyelinated axons and localization of voltage-gated sodium channels", J Neurocytol, 28 (4–5): 303–318, PMID 10739573, doi:10.1023/A:1007005528505 
  8. ^ Hewlings SJ; Sheffield-Moore, M; Cree, MG; Hewlings, SJ; Aarsland, A; Wolfe, RR; Ferrando, AA (2006), "Atrophy and impaired muscle protein synthesis during prolonged inactivity and stress", J Clin Endocrinol Metab, 91 (12): 4836–41, PMID 16984982, doi:10.1210/jc.2006-0651 

Sources[edit]