Nyoshül Khenpo Rinpoche (1932-1999), more fully Nyoshül Khenpo Jamyang Dorje (Tibetan: སྨྱོ་ཤུལ་མཁན་པོ་འཇམ་དབྱངས་རྡོ་རྗེ་, Wylie: smyo shul mkhan po 'jam dbyangs rdo rje), was a Tibetanlama born in the Derge region of Kham.
Nyoshul Khenpo Rinpoche was born in 1932 in the Derge region of Kham, Tibet. At the age of five, Rinpoche joined a Sakya monastery, in which he began his Buddhist studies. At age seventeen, he studied Longchen Nyingthig teachings and Dzogchen at the Nyoshul monastery. At the time of 1959 Tibetan uprising, when he was twenty-seven, under fire from the Chinese, he fled to India with 70 people, but only 5 arrived.