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O-1057 molecular geometry.svg
Systematic (IUPAC) name
PubChem CID 9829239
ChemSpider 8004975
Chemical data
Formula C32H46N2O4
Molar mass 522.717 g/mol

O-1057 is an analgesic cannabinoid derivative created by Organix Inc. for use in scientific research. Unlike most cannabinoids discovered to date, it is water-soluble, which gives it considerable advantages over many related cannabinoids. It has moderate affinity for both CB1 and CB2 receptors, with Ki values of 8.36 nM at CB1 and 7.95 nM at CB2.[1]

See also[edit]


  1. ^ Pertwee RG, et al. O-1057, a potent water-soluble cannabinoid receptor agonist with antinociceptive properties. British Journal of Pharmacology. 2000 Apr;129(8):1577-84. PMID 10780961