ODC1

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ODC1
Protein ODC1 PDB 1d7k.png
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases ODC1, ODC, ornithine decarboxylase 1
External IDs MGI: 97402 HomoloGene: 1906 GeneCards: ODC1
RNA expression pattern
PBB GE ODC1 200790 at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_002539
NM_001287188
NM_001287189
NM_001287190

NM_013614

RefSeq (protein)

NP_001274117
NP_001274118
NP_001274119
NP_002530

NP_038642.2
NP_038642

Location (UCSC) Chr 2: 10.44 – 10.45 Mb Chr 12: 17.54 – 17.55 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Ornithine decarboxylase is an enzyme that in humans is encoded by the ODC1 gene.

This gene encodes the rate-limiting enzyme of the polyamine biosynthesis pathway which catalyzes ornithine to putrescine. The activity level for the enzyme varies in response to growth-promoting stimuli and exhibits a high turnover rate in comparison to other mammalian proteins. Originally localized to both chromosomes 2 and 7, the gene encoding this enzyme has been determined to be located on 2p25, with a pseudogene located on 7q31-qter.[3]

References[edit]

Further reading[edit]