From Wikipedia, the free encyclopedia
Jump to: navigation, search
Olfactory receptor, family 1, subfamily E, member 1
Symbols OR1E1 ; HGM071; OR13-66; OR17-2; OR17-32; OR1E5; OR1E6; OR1E8P; OR1E9P; OST547
External IDs MGI109315 HomoloGene74111 GeneCards: OR1E1 Gene
RNA expression pattern
PBB GE OR1E1 208587 s at tn.png
PBB GE OR1E1 214515 at tn.png
More reference expression data
Species Human Mouse
Entrez 8387 258925
Ensembl ENSG00000180016 ENSMUSG00000062128
UniProt P30953 Q62343
RefSeq (mRNA) NM_003553 NM_146923
RefSeq (protein) NP_003544 NP_667134
Location (UCSC) Chr 17:
3.4 – 3.4 Mb
Chr 11:
73.35 – 73.35 Mb
PubMed search [1] [2]

Olfactory receptor 1E1 is a protein that in humans is encoded by the OR1E1 gene.[1][2][3]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[3]

See also[edit]


  1. ^ Ben-Arie N, Lancet D, Taylor C, Khen M, Walker N, Ledbetter DH, Carrozzo R, Patel K, Sheer D, Lehrach H et al. (Jul 1994). "Olfactory receptor gene cluster on human chromosome 17: possible duplication of an ancestral receptor repertoire". Hum Mol Genet 3 (2): 229–35. doi:10.1093/hmg/3.2.229. PMID 8004088. 
  2. ^ Parmentier M, Libert F, Schurmans S, Schiffmann S, Lefort A, Eggerickx D, Ledent C, Mollereau C, Gerard C, Perret J et al. (Mar 1992). "Expression of members of the putative olfactory receptor gene family in mammalian germ cells". Nature 355 (6359): 453–5. doi:10.1038/355453a0. PMID 1370859. 
  3. ^ a b "Entrez Gene: OR1E1 olfactory receptor, family 1, subfamily E, member 1". 

Further reading[edit]

External links[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.