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Olfactory receptor, family 1, subfamily E, member 2
Symbols OR1E2 ; OR17-135; OR17-136; OR17-93; OR1E4; OR1E7; OST529
External IDs MGI109312 HomoloGene128054 GeneCards: OR1E2 Gene
RNA expression pattern
PBB GE OR1E1 208587 s at tn.png
More reference expression data
Species Human Mouse
Entrez 8388 258925
Ensembl ENSG00000127780 ENSMUSG00000062128
UniProt P47887 B0QZP1
RefSeq (mRNA) NM_003554 NM_146923
RefSeq (protein) NP_003545 NP_667134
Location (UCSC) Chr 17:
3.43 – 3.43 Mb
Chr 11:
73.35 – 73.35 Mb
PubMed search [1] [2]

Olfactory receptor 1E2 is a protein that in humans is encoded by the OR1E2 gene.[1][2][3]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[3]

See also[edit]


  1. ^ Ben-Arie N, Lancet D, Taylor C, Khen M, Walker N, Ledbetter DH, Carrozzo R, Patel K, Sheer D, Lehrach H; et al. (Jul 1994). "Olfactory receptor gene cluster on human chromosome 17: possible duplication of an ancestral receptor repertoire". Hum Mol Genet 3 (2): 229–35. doi:10.1093/hmg/3.2.229. PMID 8004088. 
  2. ^ Rouquier S, Taviaux S, Trask BJ, Brand-Arpon V, van den Engh G, Demaille J, Giorgi D (Mar 1998). "Distribution of olfactory receptor genes in the human genome". Nat Genet 18 (3): 243–50. doi:10.1038/ng0398-243. PMID 9500546. 
  3. ^ a b "Entrez Gene: OR1E2 olfactory receptor, family 1, subfamily E, member 2". 

Further reading[edit]

External links[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.