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Aliases OR2A5, OR2A11P, OR2A26, OR2A8, OR7-138, OR7-141, olfactory receptor family 2 subfamily A member 5
External IDs MGI: 3030282 HomoloGene: 64846 GeneCards: OR2A5
Gene location (Human)
Chromosome 7 (human)
Chr. Chromosome 7 (human)[1]
Chromosome 7 (human)
Genomic location for OR2A5
Genomic location for OR2A5
Band 7q35 Start 144,050,368 bp[1]
End 144,051,380 bp[1]
Species Human Mouse
RefSeq (mRNA)



RefSeq (protein)



Location (UCSC) Chr 7: 144.05 – 144.05 Mb Chr 7: 42.89 – 42.9 Mb
PubMed search [3] [4]
View/Edit Human View/Edit Mouse

Olfactory receptor 2A5 is a protein that in humans is encoded by the OR2A5 gene.[5][6]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[6]

See also[edit]


  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000221836 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000043119 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:". 
  4. ^ "Mouse PubMed Reference:". 
  5. ^ Rouquier S, Taviaux S, Trask BJ, Brand-Arpon V, van den Engh G, Demaille J, Giorgi D (Mar 1998). "Distribution of olfactory receptor genes in the human genome". Nat Genet. 18 (3): 243–50. PMID 9500546. doi:10.1038/ng0398-243. 
  6. ^ a b "Entrez Gene: OR2A5 olfactory receptor, family 2, subfamily A, member 5". 

Further reading[edit]

  • Fuchs T; Malecova B; Linhart C; et al. (2003). "DEFOG: a practical scheme for deciphering families of genes". Genomics. 80 (3): 295–302. PMID 12213199. doi:10.1006/geno.2002.6830. 

External links[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.