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Aliases OR3A3, OR17-137, OR17-16, OR17-201, OR3A6, OR3A7, OR3A8P, olfactory receptor family 3 subfamily A member 3
External IDs MGI: 3030245 HomoloGene: 74999 GeneCards: OR3A3
Gene location (Human)
Chromosome 17 (human)
Chr. Chromosome 17 (human)[1]
Chromosome 17 (human)
Genomic location for OR3A3
Genomic location for OR3A3
Band 17p13.2 Start 3,420,568 bp[1]
End 3,421,533 bp[1]
RNA expression pattern
PBB GE OR3A3 221426 s at fs.png
More reference expression data
Species Human Mouse
RefSeq (mRNA)



RefSeq (protein)



Location (UCSC) Chr 17: 3.42 – 3.42 Mb Chr 17: 74.35 – 74.35 Mb
PubMed search [3] [4]
View/Edit Human View/Edit Mouse

Olfactory receptor 3A3 is a protein that in humans is encoded by the OR3A3 gene.[5][6][7]


Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[7]

See also[edit]


  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000159961 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000054406 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:". 
  4. ^ "Mouse PubMed Reference:". 
  5. ^ Ben-Arie N, Lancet D, Taylor C, Khen M, Walker N, Ledbetter DH, Carrozzo R, Patel K, Sheer D, Lehrach H (Jul 1994). "Olfactory receptor gene cluster on human chromosome 17: possible duplication of an ancestral receptor repertoire". Hum Mol Genet. 3 (2): 229–35. PMID 8004088. doi:10.1093/hmg/3.2.229. 
  6. ^ Rouquier S, Taviaux S, Trask BJ, Brand-Arpon V, van den Engh G, Demaille J, Giorgi D (Mar 1998). "Distribution of olfactory receptor genes in the human genome". Nat Genet. 18 (3): 243–50. PMID 9500546. doi:10.1038/ng0398-243. 
  7. ^ a b "Entrez Gene: OR3A3 olfactory receptor, family 3, subfamily A, member 3". 

Further reading[edit]

External links[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.