From Wikipedia, the free encyclopedia
Jump to: navigation, search
Olfactory receptor, family 5, subfamily I, member 1
Symbols OR5I1 ; HSOlf1; OLF1
External IDs OMIM608496 MGI1313139 HomoloGene4835 GeneCards: OR5I1 Gene
RNA expression pattern
PBB GE OR5I1 208521 at tn.png
More reference expression data
Species Human Mouse
Entrez 10798 258640
Ensembl ENSG00000167825 ENSMUSG00000068816
UniProt Q13606 Q7TR38
RefSeq (mRNA) NM_006637 NM_146646
RefSeq (protein) NP_006628 NP_666857
Location (UCSC) Chr 11:
55.94 – 55.94 Mb
Chr 2:
87.78 – 87.78 Mb
PubMed search [1] [2]

Olfactory receptor 5I1 is a protein that in humans is encoded by the OR5I1 gene.[1][2][3]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[3]

See also[edit]


  1. ^ Issel-Tarver L, Rine J (Apr 1997). "The Evolution of Mammalian Olfactory Receptor Genes". Genetics 145 (1): 185–95. PMC 1207777. PMID 9017400. 
  2. ^ Buettner JA, Glusman G, Ben-Arie N, Ramos P, Lancet D, Evans GA (Dec 1998). "Organization and evolution of olfactory receptor genes on human chromosome 11". Genomics 53 (1): 56–68. doi:10.1006/geno.1998.5422. PMID 9787077. 
  3. ^ a b "Entrez Gene: OR5I1 olfactory receptor, family 5, subfamily I, member 1". 

Further reading[edit]

External links[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.