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Aliases OR5I1, HSOlf1, OLF1, olfactory receptor family 5 subfamily I member 1
External IDs MGI: 1313139 HomoloGene: 4835 GeneCards: OR5I1
Gene location (Human)
Chromosome 11 (human)
Chr. Chromosome 11 (human)[1]
Chromosome 11 (human)
Genomic location for OR5I1
Genomic location for OR5I1
Band No data available Start 55,935,456 bp[1]
End 55,936,400 bp[1]
RNA expression pattern
PBB GE OR5I1 208521 at fs.png
More reference expression data
Species Human Mouse
RefSeq (mRNA)



RefSeq (protein)



Location (UCSC) Chr 11: 55.94 – 55.94 Mb Chr 11: 87.78 – 87.78 Mb
PubMed search [3] [4]
View/Edit Human View/Edit Mouse

Olfactory receptor 5I1 is a protein that in humans is encoded by the OR5I1 gene.[5][6][7]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[7]

See also[edit]


  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000167825 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000068816 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:". 
  4. ^ "Mouse PubMed Reference:". 
  5. ^ Issel-Tarver L, Rine J (Apr 1997). "The Evolution of Mammalian Olfactory Receptor Genes". Genetics. 145 (1): 185–95. PMC 1207777Freely accessible. PMID 9017400. 
  6. ^ Buettner JA, Glusman G, Ben-Arie N, Ramos P, Lancet D, Evans GA (Dec 1998). "Organization and evolution of olfactory receptor genes on human chromosome 11". Genomics. 53 (1): 56–68. PMID 9787077. doi:10.1006/geno.1998.5422. 
  7. ^ a b "Entrez Gene: OR5I1 olfactory receptor, family 5, subfamily I, member 1". 

Further reading[edit]

External links[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.