From Wikipedia, the free encyclopedia
Jump to: navigation, search
Olfactory receptor, family 5, subfamily L, member 2
Symbols OR5L2 ; HSHTPCRX16; HTPCRX16; OR11-153
External IDs MGI3030990 HomoloGene72031 GeneCards: OR5L2 Gene
RNA expression pattern
PBB GE OR5L2 gnf1h05453 s at tn.png
More reference expression data
Species Human Mouse
Entrez 26338 258814
Ensembl ENSG00000205030 ENSMUSG00000075144
UniProt Q8NGL0 A2AVC3
RefSeq (mRNA) NM_001004739 NM_146817
RefSeq (protein) NP_001004739 NP_667028
Location (UCSC) Chr 11:
55.83 – 55.83 Mb
Chr 2:
87.95 – 87.95 Mb
PubMed search [1] [2]

Olfactory receptor 5L2 is a protein that in humans is encoded by the OR5L2 gene.[1][2]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[2]

See also[edit]


  1. ^ Parmentier M, Libert F, Schurmans S, Schiffmann S, Lefort A, Eggerickx D, Ledent C, Mollereau C, Gerard C, Perret J et al. (Mar 1992). "Expression of members of the putative olfactory receptor gene family in mammalian germ cells". Nature 355 (6359): 453–5. doi:10.1038/355453a0. PMID 1370859. 
  2. ^ a b "Entrez Gene: OR5L2 olfactory receptor, family 5, subfamily L, member 2". 

Further reading[edit]

External links[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.