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Olfactory receptor, family 8, subfamily B, member 8
Symbols OR8B8 ; TPCR85
External IDs MGI2177528 HomoloGene56568 GeneCards: OR8B8 Gene
RNA expression pattern
PBB GE OR8B8 gnf1h02117 at tn.png
More reference expression data
Species Human Mouse
Entrez 26493 258310
Ensembl ENSG00000197125 ENSMUSG00000066748
UniProt Q15620 Q60882
RefSeq (mRNA) NM_012378 NM_146313
RefSeq (protein) NP_036510 NP_666425
Location (UCSC) Chr 11:
124.44 – 124.44 Mb
Chr 9:
37.9 – 37.9 Mb
PubMed search [1] [2]

Olfactory receptor 8B8 is a protein that in humans is encoded by the OR8B8 gene.[1][2]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[2]

See also[edit]


  1. ^ Vanderhaeghen P, Schurmans S, Vassart G, Parmentier M (Apr 1997). "Specific repertoire of olfactory receptor genes in the male germ cells of several mammalian species". Genomics 39 (3): 239–46. doi:10.1006/geno.1996.4490. PMID 9119360. 
  2. ^ a b "Entrez Gene: OR8B8 olfactory receptor, family 8, subfamily B, member 8". 

Further reading[edit]

External links[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.