OTOR

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OTOR
Identifiers
Aliases OTOR, FDP, MIAL1, otoraplin
External IDs MGI: 1888678 HomoloGene: 10600 GeneCards: OTOR
RNA expression pattern
PBB GE OTOR 221209 s at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_020157

NM_020595

RefSeq (protein)

NP_064542

NP_065620.1
NP_065620

Location (UCSC) Chr 20: 16.75 – 16.77 Mb Chr 2: 143.08 – 143.08 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Otoraplin is a protein that in humans is encoded by the OTOR gene.[3][4]

The protein encoded by this gene is secreted via the Golgi apparatus and may function in cartilage development and maintenance. A frequent polymorphism in the translation start codon of this gene can abolish translation and may be associated with forms of deafness. This gene is a member of the melanoma-inhibiting activity gene family. In addition, alternate polyA sites exist for this gene.[4]

References[edit]

  1. ^ "Human PubMed Reference:". 
  2. ^ "Mouse PubMed Reference:". 
  3. ^ Robertson NG, Heller S, Lin JS, Resendes BL, Weremowicz S, Denis CS, Bell AM, Hudspeth AJ, Morton CC (Sep 2000). "A novel conserved cochlear gene, OTOR: identification, expression analysis, and chromosomal mapping". Genomics. 66 (3): 242–8. doi:10.1006/geno.2000.6224. PMID 10873378. 
  4. ^ a b "Entrez Gene: OTOR otoraplin". 

Further reading[edit]