From Wikipedia, the free encyclopedia
Jump to: navigation, search
Oxoglutarate (alpha-ketoglutarate) receptor 1
Symbols OXGR1 ; GPR80; GPR99; P2RY15; P2Y15; aKGR
External IDs OMIM606922 MGI2685145 HomoloGene25878 IUPHAR: 162 GeneCards: OXGR1 Gene
RNA expression pattern
PBB GE OXGR1 gnf1h10308 at fs.png
More reference expression data
Species Human Mouse
Entrez 27199 239283
Ensembl ENSG00000165621 ENSMUSG00000044819
UniProt Q96P68 Q6IYF8
RefSeq (mRNA) NM_080818 NM_001001490
RefSeq (protein) NP_543008 NP_001001490
Location (UCSC) Chr 13:
96.99 – 96.99 Mb
Chr 14:
120.02 – 120.04 Mb
PubMed search [1] [2]

2-oxoglutarate receptor 1 is a protein that in humans is encoded by the OXGR1 gene.[1][2][3]

G protein-coupled receptors (GPCRs, or GPRs) contain 7 transmembrane domains and transduce extracellular signals through heterotrimeric G proteins.[supplied by OMIM][3]


  1. ^ He W, Miao FJ, Lin DC, Schwandner RT, Wang Z, Gao J, Chen JL, Tian H, Ling L (May 2004). "Citric acid cycle intermediates as ligands for orphan G-protein-coupled receptors". Nature 429 (6988): 188–93. doi:10.1038/nature02488. PMID 15141213. 
  2. ^ Wittenberger T, Hellebrand S, Munck A, Kreienkamp HJ, Schaller HC, Hampe W (Jul 2003). "GPR99, a new G protein-coupled receptor with homology to a new subgroup of nucleotide receptors". BMC Genomics 3: 17. doi:10.1186/1471-2164-3-17. PMC 117779. PMID 12098360. 
  3. ^ a b "Entrez Gene: OXGR1 oxoglutarate (alpha-ketoglutarate) receptor 1". 

Further reading[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.