The sanatorium, built in the Kanzaki River delta valley, was hit by the Muroto typhoon on September 21, 1934. The storm left 2,702 dead and 334 missing, including 187 people in the sanatorium (173 patients, 3 employees, and 11 family members). On September 24, 1934, the Interior Ministry decided to transfer 416 survivors to other sanatoriums, including Nagashima Aiseien Sanatorium (78 patients), Kyushu Sanatorium (Kikuchi Keifuen Sanatorium) (50 patients), Ooshima Sanatorium (70 patients), Zensho Byoin (Tama Zenshoen Sanatorium (70 patients), Hokubu Hoyoen Sanatorium (50 patients), and Kuryu Rakusen-en Sanatorium (98 patients).
The number of inpatients in a given year depends not only on those newly hospitalized and the recently deceased, but also on other factors such as patient escapes and discharges, depending on the conditions of the times. Recently, the sanatorium was encouraged to discharge patients[by whom?], but a long-standing segregation and the resulting stigma against leprosy patients might have influenced the number of patients discharged.