It acts as a stabilized, less volatile form of hydrogen fluoride. It is used in the fluorination of steroids and in deprotection of peptides. Instead of hydrogen fluoride, several other fluorinating agents can be used, such as diethylaminosulfur trifluoride (DAST).
- C. G. Bergstrom et al., J. Org. Chem. 28, 2633 (1963)
- G. A. Olah et al., Synthesis 1973, 779; idem et al., J. Org. Chem. 44, 3872 (1979).
- Review of use in organic synthesis: G. A. Olah et al., J. Fluorine Chem. 33, 377–396 (1986).