Olfactory glands

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Olfactory glands
Section of the olfactory mucous membrane.
Latin glandulae olfactoriae
Gray's p.996
Code TH H3.
TA A15.1.00.001
FMA 77659
Anatomical terminology

Bowman's glands (a.k.a. olfactory glands, glands of Bowman) are situated in the olfactory mucosa, beneath the olfactory epithelium, in the lamina propria, a connective tissue also containing fibroblasts, blood vessels, and bundles of fine axons from the olfactory neurons.[1]

The structure of the Bowman's glands consists of an acinus in the lamina propria and a secretory duct going out through the olfactory epithelium.

Electron microscopy studies show that Bowman's glands contain cells with large secretory vesicles.[2] Bowman's glands secrete the gel-forming mucin MUC5AC(UniProtKB: P98088).[3] Bowman's glands might secrete proteins such as lysozyme, amylase and IgA similarly to serous glands. The exact composition of the secretions from Bowman's glands is unclear, but there is evidence that Bowman's glands do not produce odorant binding protein.[4]

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This article incorporates text in the public domain from the 20th edition of Gray's Anatomy (1918)

  1. ^ Moran, David T.; Rowley Jc, 3rd; Jafek, BW; Lovell, MA (1982), "The fine structure of the olfactory mucosa in man", Journal of Neurocytology 11 (5): 721–746, doi:10.1007/BF01153516, PMID 7143026 
  2. ^ Frisch, Donald (1967), "Ultrastructure of mouse olfactory mucosa.", The American Journal of Anatomy 121 (1): 87–120., doi:10.1002/aja.1001210107, PMID 6052394 
  3. ^ Solbu, T. T.; Holen, T. (2012), "Aquaporin pathways and mucin secretion of Bowman's glands might protect the olfactory mucosa.", Chemical Senses 37 (1): 35–46., doi:10.1093/chemse/bjr063, PMID 21745799 
  4. ^ Tegoni, Mariella; Pelosi, P; Vincent, F; Spinelli, S; Campanacci, V; Grolli, S; Ramoni, R; Cambillau, C (2000), "Mammalian odorant binding proteins", Biochimica et Biophysica Acta (1967) 1482 (1–2): 229–240., doi:10.1016/S0167-4838(00)00167-9, PMID 11058764 

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