Oligotyping (taxonomy)

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Oligotyping is a diagnostic or molecular biological method for classification of organisms by short intervals of primary DNA sequence.

Oligotyping 'systems' are sets of recognized target sequences which identify the members of the categories within the classification. The classification may be for the purpose of primary biological taxonomy, or for a functional classification.

Classifying bacteria[edit]

Oligotyping has been used for classifying bacteria,[1] identifying bacterial antibiotic resistance genes,[2] identifying genetic factors in human infectious disease,[3] and performing histocompatibility tests for human blood or bone marrow donors/recipients .

See also[edit]


  1. ^ Roring, S; Brittain, D; Bunschoten, A. E; Hughes, M. S; Skuce, R. A; van Embden, J. D. A; Neill, S. D (15 March 1998). "Spacer oligotyping of Mycobacterium bovis isolates compared to typing by restriction fragment length polymorphism using PGRS, DR and IS6110 probes". Veterinary Microbiology. 61 (1–2): 111–120. doi:10.1016/S0378-1135(98)00178-3.
  2. ^ Mabilat, C.; Courvalin, P. (1 November 1990). "Development of "oligotyping" for characterization and molecular epidemiology of TEM beta-lactamases in members of the family Enterobacteriaceae". Antimicrobial Agents and Chemotherapy. 34 (11): 2210–2216. doi:10.1128/AAC.34.11.2210. ISSN 0066-4804. PMC 172024. PMID 2073111.
  3. ^ Rani, Rajni; Fernandez-Vina, M. A.; Zaheer, S. A.; Beena, K. R.; Stastny, Peter (1 July 1993). "Study of HLA class II alleles by PCR oligotyping in leprosy patients from North India". Tissue Antigens. 42 (1): 133–137. doi:10.1111/j.1399-0039.1993.tb02179.x. ISSN 1399-0039. PMID 8284786.