Optic nerve glioma

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Optic nerve glioma
Optic glioma.jpg
Magnetic resonance image of a large retrobulbar optic nerve tumor causing massive proptosis
SpecialtyOncology Edit this on Wikidata

Optic nerve glioma (or optic glioma), a form of glioma which affects the optic nerve, is often one of the central nervous system manifestations of neurofibromatosis 1.[1][2]

Optic gliomas are usually pilocytic tumors, and can involve the optic nerve or optic chiasm.[3] Optic gliomas are usually associated with neurofibromatosis type 1 in 30% of patients.[3]



While radiation or chemotherapy may be helpful, treatment is often not necessary.[3] Optical gliomas often cannot be surgically resected. If no visual symptoms wait 6 months and then in 6 months only treat if there are symptoms (visual loss, eye pain), otherwise do not treat.[3]


Optic gliomas often have a shifting clinical course, with sporadic periods of vision loss separated by long periods of visual stability.[3] Optic gliomas rarely spontaneously regress.[3]


  1. ^ Huson, Susan Mary; Hughes, Richard Anthony Cranmer (1994). The neurofibromatoses: a pathogenetic and clinical overview. London: Chapman & Hall. 1.3.2:9. ISBN 0-412-38920-7.
  2. ^ Skelley, Tao Le, Vikas Bhushan, Nathan William. First aid for the USMLE step 2 CK (8th ed.). New York: McGraw-Hill Medical. ISBN 978-0-07-176137-6.
  3. ^ a b c d e f Goldman, Lee. Goldman's Cecil Medicine (24th ed.). Philadelphia: Elsevier Saunders. p. 1251. ISBN 1437727883.

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