Administratively the island belongs to Holbæk Municipality.
There are four villages on Orø: Bybjerg, the largest village on the island with a population of 248 (1 January 2013), Brønde, Gamløse and Næsby.
It is a popular vacation area with some 1,200 summer houses.
Orø Church dating back to the 12th century and Orø Museum depicting local life in the area are national monuments.
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