Oral mite anaphylaxis

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Oral mite anaphylaxis (OMA), also known as pancake syndrome, is a disease in which a person gets symptoms after eating food contaminated with particular mites. The disease name comes from reports of people becoming ill after eating pancakes made from contaminated flour.

Mites suspected as causing the condition are Dermatophagoides pteronyssinus, Blomia tropicalis, and Suidasia pontifica (Suidasia medanensis).[1] The latter two are the most likely to have caused the harmful effects, and they live in tropical and subtropical environments.[1]

Because the disease is transmitted by pancakes and other cooked food, scientists expect that this means that the allergen can withstand the heat of cooking.[2] Storing flour at low temperature in a freezer could prevent contamination or kill existing mites in the flour.[2] Anaphylaxis can occur during exposure to NSAID drugs or exercise to those exposed to the mites.[1][2]

Further reading[edit]

  • Mangodt, EA; Van Gasse, AL; Bridts, CH; Sabato, V; Ebo, DG (2015). "Simultaneous oral mite anaphylaxis (pancake syndrome) in a father and daughter and a review of the literature". Journal of Investigational Allergology & Clinical Immunology. 25 (1): 75–6. PMID 25898706.
  • Sánchez-Borges, Mario; Capriles-Hulett, Arnaldo; Caballero-Fonseca, Fernan (2008). "ADDITIONAL INFORMATION ON THE PANCAKE SYNDROME". Annals of Allergy, Asthma & Immunology. 101 (2): 221. doi:10.1016/S1081-1206(10)60215-3. ISSN 1081-1206.
  • Sánchez-Borges, M; Capriles-Hulett, A; Caballero-Fonesca, F (May 2006). "Oral mite anaphylaxis (pancake syndrome) also observed in children". Annals of Allergy, Asthma & Immunology. 96 (5): 755–6. doi:10.1016/s1081-1206(10)61079-4. PMID 16729794.
  • Hashizume, H.; Umayahara, T.; Kawakami, Y. (January 2014). "Pancake syndrome induced by ingestion of tempura". British Journal of Dermatology. 170 (1): 213–214. doi:10.1111/bjd.12597.
  • Hannaway, Paul J.; Miller, Jeffrey D. (2008). "THE PANCAKE SYNDROME (ORAL MITE ANAPHYLAXIS) BY INGESTION AND INHALATION IN A 52-YEAR-OLD WOMAN IN THE NORTHEASTERN UNITED STATES". Annals of Allergy, Asthma & Immunology. 100 (4): 397–398. doi:10.1016/S1081-1206(10)60607-2. ISSN 1081-1206.
  • Sánchez-Borges, Mario; Fernandez-Caldas, Enrique (2015). "Hidden allergens and oral mite anaphylaxis". Current Opinion in Allergy and Clinical Immunology. 15 (4): 337–343. doi:10.1097/ACI.0000000000000175. ISSN 1528-4050.


  1. ^ a b c Barrera, OM; Murgas, IL; Bermúdez, S; Miranda, RJ (June 2015). "[Oral anaphylaxis by ingestion of mite contaminated food in Panama City, 2011-2014]". Revista Alergia Mexico. 62 (2): 112–7. PMID 25958374.
  2. ^ a b c Sánchez-Borges, M; Suárez-Chacon, R; Capriles-Hulett, A; Caballero-Fonseca, F; Iraola, V; Fernández-Caldas, E (May 2009). "Pancake syndrome (oral mite anaphylaxis)". The World Allergy Organization Journal. 2 (5): 91–6. doi:10.1097/wox.0b013e3181a0db50. PMC 3651046. PMID 23283016.