Just south of the station, the line from Adelaide becomes single track for the remainder of the journey to Outer Harbor. It once had two platforms but one closed in the 1980s when the balloon loop north was removed. The level crossing next to the station has the remnants of the second track still visible. Just south of the station, a line branched off to the ICI Osborne works, this has since been dismantled.
Some peak hour services from Adelaide terminate at Osborne.