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Osmeña is a family name of the Philippines. It may refer to:
- Sergio Osmeña (1878–1961), President
- Sergio Osmeña, Jr. (1918–1984), Senator
- John Henry Osmeña (1935– ), Senator
- Emilio Mario Osmeña (1938– ), Governor of Cebu
- Sergio Osmeña III (1943– ), Senator
- Tomas Osmeña (1948– ), Mayor of Cebu City
It may also refer to:
- Sergio Osmeña Sr., Zamboanga del Norte, a municipality in the Philippines
- Osmeña perl, a jewelry product derived from the chambered Nautilus
|This disambiguation page lists articles associated with the title Osmeña.
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