Ovarian follicle atresia
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||It has been suggested that this article be merged with Follicular atresia. (Discuss) Proposed since September 2014.|
Ovarian follicle atresia is the periodic process in which immature ovarian follicles degenerate and are subsequently re-absorbed during the follicular phase of the menstrual cycle. Typically around 20 follicles mature each month but only a single follicle is ovulated. The rest undergo atresia. That single dominant follicle becomes a corpus luteum following ovulation.
- tumor necrosis factor alpha (TNF alpha) and receptors
- Fas ligand and receptors
- TNF-related apoptosis-inducing ligand (TRAIL; also called APO-2) and receptors
- APO-3 ligand and receptors
- PFG-5 ligand and receptors
In addition, two intracellular inhibitor proteins, cellular FLICE-like inhibitory protein short form (cFLIPS) and long form (cFLIPL), which were strongly expressed in granulosa cells, may act as anti-apoptotic factors.
- Advanced maternal age
- Female infertility
- Ovarian follicle
- Ovarian reserve
- Ovarian Aging
- Premature ovarian failure
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