From Wikipedia, the free encyclopedia
  (Redirected from Oxytocic)
Jump to navigation Jump to search

A uterotonic, also known as ecbolic, is an agent used to induce contraction or greater tonicity of the uterus. Uterotonics are used both to induce labor, and to reduce postpartum hemorrhage.

Some uterotonics act as analogues of oxytocin (OXT). An oxytocinergic or oxytocic chemical pathway is one responding to oxytocin or its analogues, and an oxytocinergic or oxytocic agent is any of these agents, oxytocin or its analogues, with similar physiologic effect, chemical interaction, or (usually) both. The oxytocin receptor (OXTR) is the binding and activation site of oxytocin.

Some agents may act as indirect oxytocinergics:

Analogs of oxytocin
  • Conversely, a tocolytic acts to oppose uterine contractility. These agents may be oxytocinergic in mechanism. For example, atosiban works in this way.
Natural food
  • Parsley in large amount may have uterotonic effect

See also[edit]


  1. ^ Nagashima, Renpei; Takano, Noboru; Tamura, Masaaki; Shioya, Akitoshi (1966). "PHARMACOLOGICAL PROPERTIES OF 3-(p-CHLOROBENZYL) QUINOLIZIDINE TARTARATE (QB-1), A NEW OXYTOCIC". The Japanese Journal of Pharmacology. 16 (4): 353–367. doi:10.1254/jjp.16.353. ISSN 0021-5198.
  2. ^ Elks, J.; Ganellin, C. R. (1990). "Dictionary of Drugs". doi:10.1007/978-1-4757-2085-3. ISBN 978-1-4757-2087-7.
  3. ^ https://www.openanesthesia.org/aba_oxytocic_drugs_-_indications/
  4. ^ Garcia-Villar, R.; Marnet, P.G.; Laurentie, M.P.; Toutain, P.L. (1987). "Fenprostalene in cattle: Evaluation of oxytocic effects in ovariectomized cows and abortion potential in a 100-day pregnant cow". Theriogenology. 28 (4): 467–480. doi:10.1016/0093-691X(87)90251-2. ISSN 0093-691X.

External links[edit]