Ozzy & Drix

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Ozzy & Drix
Ozzy and Drix.jpg
Based on Osmosis Jones by Peter Farrelly, Bobby Farrelly , and Marc Hyman
Developed by Peter Farrelly
Marc Hyman
Narrated by Phil LaMarr
Opening theme "Ozzy & Drix"
Country of origin United States
Original language(s) English
No. of seasons 2
No. of episodes 26 (list of episodes)
Executive producer(s)
Running time 22 minutes
Production company(s)
Original network Kids' WB
Original release September 14, 2002 (2002-09-14) – July 5, 2004 (2004-07-05)
Preceded by Osmosis Jones

Ozzy & Drix is an American animated television series based on the Warner Bros. film Osmosis Jones and produced by Warner Bros. Animation. It takes place inside the body of teenager Hector Cruz (referred to by the characters as "the City of Hector"). The series premiered on September 14, 2002 on the Kids' WB; the final episode aired July 5, 2004. Unlike the original film it spun off from, Ozzy & Drix was entirely animated and contained no live action. It stars Phil LaMarr as the replacement for Chris Rock as Osmosis Jones, and Jeff Bennett as the replacement for David Hyde Pierce as Drix.

As of July 2011, episodes of the series were still available via the Kids WB website. It also aired reruns on Cartoon Network from October 4, 2004 to September 22, 2006.


A year after Ozzy and Drix defeated Thrax and saved Frank from dying in Osmosis Jones, Ozzy and Drix chase a scarlet fever bacterium (possibly thanks to Frank resuming his poor eating habits). During the chase, Ozzy, Drix and the germ get sucked up from Frank by a mosquito and arrive on a Cuban American teenager named Hector Cruz. After some initial problems with their new home, both are installed as Private Investigators, vowing to protect Hector's well being from any viral threat, not to mention, help him through the changes in his teen years.

The show is also slightly less violent than the movie, having the characters treated like people rather than simply cells, and having none of them killed off, unlike the movie where Thrax managed to kill off several cells. There are also new characters that replace the ones from the original movie such as Maria Amino replacing Leah Estrogen, Mayor Spryman replacing Mayor Phlegmming, Chief Gluteus replacing The Chief of Police, The Mole replacing Chill the Flu Shot and the new villains replacing Thrax. The show was created by the Farelly Brothers, who also directed the live action portion of the film.


Main characters[edit]

Recurring characters[edit]

Series overview[edit]

Season Episodes Originally aired
First aired Last aired
1 13 September 14, 2002 (2002-09-14) March 1, 2003 (2003-03-01)
2 13 August 23, 2003 (2003-08-23) July 5, 2004 (2004-07-05)


Note: Several episodes borrow footage from its film counterpart, Osmosis Jones. Most notably the episode, Auntie Histamine.

Season 1 (2002–03)[edit]

No. Title Original air date
1 "Home With Hector" September 14, 2002 (2002-09-14)
By way of a simple mosquito bite, Ozzy and Drix are transferred from Frank Detorre and into the body of a teenage boy named Hector Cruz. A nasty germ named Scarlet Fever is also transferred. Ozzy and Drix must capture him before he wreaks havoc on the City of Hector.
2 "Reflex" September 21, 2002 (2002-09-21)
Ozzy accidentally produces a neural spasm that causes Hector to kick Ricky the school bully. When Rick threatens to beat up Hector after school, Ozzy has to figure out a way to help Hector defend himself. But that'll be hard when he gets put in the slammer.
3 "Strep-Finger" September 28, 2002 (2002-09-28)
Ozzy becomes jealous of a super agent (Penicillin G.) who has been injected into Hector to track down a powerful germ known as Strepfinger.
4 "A Lousy Haircut" October 5, 2002 (2002-10-05)
When Ozzy discovers there are lice eggs in Hector's hair, he and Drix venture onto the scalp to knock the eggs off, only to end up running into the Mother Louse. When Ozzy starts coagulating, Drix has to stop the lice and save Ozzy all at once.
5 "Oh, My Dog" October 12, 2002 (2002-10-12)
Drix's new pet dog, Dander, is mistaken for an Allergen that is threatening the city, while, outside Hector, Mrs. Cruz thinks that it is Hector's dog causing the allergy that Hector is suffering from.
6 "Street Up" October 19, 2002 (2002-10-19)
Drix tries to learn how to act "street" and ends up helping an acne germ create a huge zit on Hector's face just in time for picture day.
7 "Gas of Doom" November 9, 2002 (2002-11-09)
Ozzy, Drix, and Maria commandeer a submersible police craft into the intestines to stop a gas build-up that threatens Hector's social situation and infects him with gastroenteritis. Maria is desperate to stop the build up because one gas attack Hector had killed her father and she's determined to avenge him. However, the Rota Virus captures her and ties her up with rope and struggles to get free.
8 "Where There's Smoke" November 16, 2002 (2002-11-16)
Ozzy must keep Nick O'Teen from getting to the brain where he will cause Hector to smoke. However, Nick and his henchmen kidnap him, Drix, the Chief, and Spryman and takes over Hector's brain. Christine tries to warn Hector about the evils of smoking, but he doesn't listen to her.
9 "The Globfather" November 30, 2002 (2002-11-30)
Hector eats a "rusty dog" from the rusty dog stand and gets salmonella. Now Ozzy and Drix has to save the day and the mayor from the toxic germ Sal Monella.
10 "Ozzy Jr." December 7, 2002 (2002-12-07)
Ozzy thinks he is having a baby, but it turns out to be an infection from an intracellular bacteria by returning villain Strepfinger. Ozzy and Drix must find a way to destroy the parasite growing within Ozzy before it spreads its infection to all of Hector. The parasite grows to monstrous proportions, exits Ozzy, and is eventually destroyed when Drix finds it is killed by pastry products.
11 "Growth" February 1, 2003 (2003-02-01)
The Mayoral election is coming up, and Spryman's opponent, a nerdy brain cell named Sylvian Fisher, is using a secret growth formula to cause destructive unnatural growth spurts and make the Mayor look bad. Ozzy and Drix must stop this fiendish plan, which becomes more difficult when Sylvian takes the growth formula himself and becomes a raging, muscular monster.
12 "Sugar Shock" February 8, 2003 (2003-02-08)
Hector binges on candy, creating a sugar rush that speeds up all the cells and causes the bacteria population to swell. When his parents cut him off sugar as a result of this, his drop in blood sugar slows all the cells to a crawl. But the bacteria need sugar, so they form an army to raid Hector's sugar reserves. Now Drix and an extremely sleepy Ozzy, with the help of the Mole, must take on the bacterial army.
13 "The Dream Factory" March 1, 2003 (2003-03-01)
Hector experiences recurring nightmares after seeing a scary movie, keeping everyone in the City of Hector awake. Ozzy and Drix go to the "Subconscious Network," where dreams are produced, and enter Hector's nightmare to help him face his fear. However, whatever happens to Ozzy and Drix in the dream happens for real.

Season 2 (2003–04)[edit]

No. Title Original air date
14 "An Out of Body Experience Part 1" August 23, 2003 (2003-08-23)
Ozzy accidentally gets transferred into Christine's body when she gives Hector CPR after he jumps off the high dive to impress her. While there, Ozzy starts changing colors and acting like a girl and gets arrested because they think he is a virus.
15 "An Out of Body Experience Part 2" August 30, 2003 (2003-08-30)
While Ozzy is still in Christine, using REM sleep (or Rapid Eye Movement), he calls Drix for help, and that's when he learns he's gender morphing. When a cell from a certain gender goes to a body of another gender, that cell becomes that gender. With Drix's plan, and the help of another Drixinol cold pill in Christine called "Drixina," Ozzy comes back to Hector, and keeps Christine from having pneumonia.
16 "Lights Out!" September 6, 2003 (2003-09-06)
Everyone inside Hector forgets who Ozzy and Drix are when Hector experiences a concussion, forcing them to locate the site of the concussion, so they can reboot Hector's memories before Hector crashes.
17 "The Conqueror Worm" September 13, 2003 (2003-09-13)
Hector eats a barely cooked sausage and gets sick to his stomach, leading him to getting two worms Trichinella spiralis in his body. The male worm dies, but the female survives. Ozzy, Drix, and a crazy captain must try to kill it before Hector's stomach is destroyed.
18 "Puberty Alert" September 20, 2003 (2003-09-20)
When Hector discovers hair growing on his chin; the testosterone gang ties up the Mayor and wreaks havoc, causing Hector to get into trouble, especially when sneaking out to an all night party in a dangerous part of town when his parents forbid it. It's up to Ozzy and Drix to stop the testosterone gang and save the Mayor before Hector gets in even more trouble.
19 "Tricky Ricardo" September 27, 2003 (2003-09-27)
After getting injured on a police case, Maria is sent home to rest for the week. She decided to use this time to work on a family reunion coming up for her. Drix notices a rip on the corner of Maria's family picture. Maria does not seem to want to talk about it but then her brother, Ricky comes in and starts putting the puzzle pieces together. Maria and Ricky share their past with Drix which turns out as Ricky being the family prankster. Maria lost her trust in him so Drix decides to help Ricky get it back. He allows him to be a private eye along with Ozzy with good results and Ricky actually becomes one of the best. Unfortunately, Ricky is working for Strepfinger, who plots to create a tumor out of Drix's medications, but now Ricky is reluctant to hurt Maria again.
20 "Aunti Histamine" October 4, 2003 (2003-10-04)
Hector uses a nose spray to clear his nose, and Drix's aunt appears. Suddenly, Hector's water levels drop and Ozzy realizes Drix's aunt is causing it, thanks to Hector's carelessness.
21 "A Growing Cell" October 11, 2003 (2003-10-11)
Hector is super-sizing at fast-food restaurants too much which not only makes him a little chubby, but it also gives Stickety Lipid, a bad cholesterol beatnik, the chance to kidnap a fat cell family's child, in an attempt to cause a massive coronary. Ozzy and Drix (and the new navigational system, installed by Drix, named Backseat) must return the huge blob to his parents in time. Hector must also get in better shape.
22 "A Cold Day In Hector" February 25, 2004 (2004-02-25)
While snowboarding with Travis, Hector crosses an off limits area. Hector starts to freeride, but falls and rips his snowsuit. This causes a virus named Cryo to drop Hector's temperature. Ozzy and Drix were getting ready for a day at the beach, but now have to stop Cryo from making Hector die of hypothermia.
23 "Supplements (aka Triumph of The Supplements)" June 14, 2004 (2004-06-14)
When Hector accidentally breathes in lead while helping his dad strip old paint off of a shed, the Lead Gang cause him to feel ill. Drix then makes Hector eat cereal so he can bring in the Supplements who ask him to be their sidekick.
24 "Double Dose" June 21, 2004 (2004-06-21)
Ozzy goes into mitosis and a four armed evil clone doubles from him, trying to steal the iodine that will allow Hector to grow.
25 "Nature Calls" June 28, 2004 (2004-06-28)
Billy Bob Bile creates a detour away from the small intestine so bacteria will come to his hotel. Ozzy, Drix, and Maria, who are camping and forced to work at the hotel, must stop Bile before Hector's appendix bursts.
26 "Journey To The Center of The Tooth" July 5, 2004 (2004-07-05)
After Hector eats excessive sugar without brushing his teeth, he gets a cavity caused by General Malaise. Malaise plans to cause further pain when Hector goes to the dentist. Meanwhile, Drix must overcome his claustrophobia.

External links[edit]