|City & municipal seat|
|Founded||22 December 1522|
|City status||30 June 1931|
|• Municipal President||Ricardo García Guzmán|
|Elevation||10 m (30 ft)|
Pánuco ( 'panuko (help·info)) is a city in the Mexican state of Veracruz, located in the state's Huasteca Alta region. It serves as the municipal seat of the surrounding Pánuco Municipality. It stands on the banks of the Río Pánuco.
In the 2005 INEGI Census, the city of Pánuco reported a total population of 33,122.
Pánuco is traditionally held to have been founded by Hernán Cortés on 22 December 1522, as Villa de Santiesteban del Puerto, the second ayuntamiento on the American continent. It was the capital of the Province of Pánuco in the early colonial period. It was given city status on 30 June 1931.
Hernando de Soto's expedition stopped in Panuco after his death.
- "Pánuco". Enciclopedia de los Municipios de México. Instituto Nacional para el Federalismo y el Desarrollo Municipal. Retrieved 2 November 2008.
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