Pål Nyrén

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Pål Nyrén (born 1955) is a biochemistry professor at the Royal Institute of Technology (KTH), Stockholm.[1] He is most famous for developing the pyrosequencing method for DNA sequencing.[2][3]


  • 1999 Professor in Biochemistry, KTH, Stockholm
  • 1997 Founder of the company Biotage AB (former Pyrosequencing AB)
  • 1988 Associate professor (Docent) Biochemistry, University of Stockholm
  • 1985-86 Postdoc at LMB, MRC, Cambridge, G.B. with prof John Walker
  • 1985 Ph.D. (Tekn. Doktor) Biochemistry, University of Stockholm (Thesis title: "The proton pumping pyrophosphatase from Rhodospirillum rubrum")
  • 1981 M.Sc. (Civ. ing.) Chemical Engineering, KTH, Stockholm



  1. ^ "Royal Institute of Technology: Pål Nyrén". Archived from the original on 29 June 2009. Retrieved 10 May 2010. 
  2. ^ Nyren, Petersson and Uhlen (1993) “Solid Phase DNA Minisequencing by an Enzymatic Luminometric Inorganic Pyrophosphate Detection Assay” Analytical Biochemistry 208 (1), 171-175, https://doi.org/10.1006/abio.1993.1024
  3. ^ Ronaghi, Uhlén and Nyrén (1998) ”A sequenbcing method based on real-time pyrophosphate” Science. 281 (5375): 363. https://doi.org/10.1126/science.281.5375.363
  4. ^ Invention: Pyrosequencing