PIK3CB

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PIK3CB
Identifiers
Aliases PIK3CB, P110BETA, PI3K, PI3KBETA, PIK3C1, phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
External IDs MGI: 1922019 HomoloGene: 21250 GeneCards: PIK3CB
Targeted by Drug
idelalisib, ly-294002[1]
RNA expression pattern
PBB GE PIK3CB 212688 at tn.png

PBB GE PIK3CB 217620 s at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001256045
NM_006219

NM_029094

RefSeq (protein)

NP_001242974
NP_006210

NP_083370.2
NP_083370

Location (UCSC) Chr 3: 138.65 – 138.83 Mb Chr 9: 99.04 – 99.14 Mb
PubMed search [2] [3]
Wikidata
View/Edit Human View/Edit Mouse

Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta isoform is an enzyme that in humans is encoded by the PIK3CB gene.[4][5]

Phosphoinositide 3-kinases (PI3Ks) phosphorylate the 3-prime OH position of the inositol ring of inositol lipids. They have been implicated as participants in signaling pathways regulating cell growth by virtue of their activation in response to various mitogenic stimuli. PI3Ks are composed of a 110-kD catalytic subunit, such as PIK3CB, and an 85-kD adaptor subunit (Hu et al., 1993).[supplied by OMIM][5]

References[edit]

Further reading[edit]