P2RX5

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P2RX5
Identifiers
AliasesP2RX5, LRH-1, P2X5, P2X5R, purinergic receptor P2X 5
External IDsMGI: 2137026 HomoloGene: 1924 GeneCards: P2RX5
Gene location (Human)
Chromosome 17 (human)
Chr.Chromosome 17 (human)[1]
Chromosome 17 (human)
Genomic location for P2RX5
Genomic location for P2RX5
Band17p13.2Start3,672,199 bp[1]
End3,696,404 bp[1]
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_175081
NM_001204519
NM_001204520
NM_002561
NM_175080

NM_033321

RefSeq (protein)

NP_001191448
NP_001191449
NP_002552
NP_778255

n/a

Location (UCSC)Chr 17: 3.67 – 3.7 MbChr 11: 73.16 – 73.17 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

P2X purinoceptor 5 is a protein that in humans is encoded by the P2RX5 gene.[5][6]

The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel. Several characteristic motifs of ATP-gated channels are present in its primary structure, but, unlike other members of the purinoceptors family, this receptor has only a single transmembrane domain. Four transcript variants encoding distinct isoforms have been identified for this gene.[6]

See also[edit]

References[edit]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000083454 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000005950 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:". 
  4. ^ "Mouse PubMed Reference:". 
  5. ^ Le KT, Paquet M, Nouel D, Babinski K, Seguela P (Jan 1998). "Primary structure and expression of a naturally truncated human P2X ATP receptor subunit from brain and immune system". FEBS Lett. 418 (1–2): 195–9. doi:10.1016/S0014-5793(97)01380-X. PMID 9414125. 
  6. ^ a b "Entrez Gene: P2RX5 purinergic receptor P2X, ligand-gated ion channel, 5". 

Further reading[edit]

External links[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.