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Purinergic receptor P2Y, G-protein coupled, 14
Available structures
PDB Ortholog search: PDBe, RCSB
Symbols P2RY14 ; BPR105; GPR105; P2Y14
External IDs OMIM610116 MGI2155705 HomoloGene15769 IUPHAR: 330 ChEMBL: 4518 GeneCards: P2RY14 Gene
RNA expression pattern
PBB GE P2RY14 206637 at tn.png
More reference expression data
Species Human Mouse
Entrez 9934 140795
Ensembl ENSG00000174944 ENSMUSG00000036381
UniProt Q15391 Q9ESG6
RefSeq (mRNA) NM_001081455 NM_001008497
RefSeq (protein) NP_001074924 NP_001008497
Location (UCSC) Chr 3:
151.21 – 151.28 Mb
Chr 3:
59.11 – 59.15 Mb
PubMed search [1] [2]

P2Y purinoceptor 14 is a protein that in humans is encoded by the P2RY14 gene.[1]

The product of this gene, P2Y14 belongs to the family of G-protein coupled receptors, which contains several receptor subtypes with different pharmacological selectivity for various adenosine and uridine nucleotides. This receptor is a P2Y purinergic receptor for UDP-glucose and other UDP-sugars coupled to G-proteins. It has been implicated in extending the known immune system functions of P2Y receptors by participating in the regulation of the stem cell compartment, and it may also play a role in neuroimmune function. Two transcript variants encoding the same protein have been identified for this gene.[1]

See also[edit]


Further reading[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

External links[edit]

  • "P2Y Receptors: P2Y14". IUPHAR Database of Receptors and Ion Channels. International Union of Basic and Clinical Pharmacology.