P2RY4

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P2RY4
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesP2RY4, NRU, P2P, P2Y4, UNR, pyrimidinergic receptor P2Y4
External IDsMGI: 1926594 HomoloGene: 20568 GeneCards: P2RY4
Gene location (Human)
X chromosome (human)
Chr.X chromosome (human)[1]
X chromosome (human)
Genomic location for P2RY4
Genomic location for P2RY4
BandXq13.1Start70,258,170 bp[1]
End70,259,764 bp[1]
RNA expression pattern
PBB GE P2RY4 221466 at fs.png
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_002565

NM_020621

RefSeq (protein)

NP_002556

NP_065646

Location (UCSC)Chr X: 70.26 – 70.26 MbChr X: 100.59 – 100.59 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

P2Y purinoceptor 4 is a protein that in humans is encoded by the P2RY4 gene.[5][6]

The product of this gene, P2Y4, belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is responsive to uridine nucleotides, partially responsive to ATP, and not responsive to ADP.[6]

See also[edit]

References[edit]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000186912 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000044359 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:". 
  4. ^ "Mouse PubMed Reference:". 
  5. ^ Communi D, Pirotton S, Parmentier M, Boeynaems JM (Feb 1996). "Cloning and functional expression of a human uridine nucleotide receptor". J Biol Chem. 270 (52): 30849–52. doi:10.1074/jbc.270.52.30849. PMID 8537336. 
  6. ^ a b "Entrez Gene: P2RY4 pyrimidinergic receptor P2Y, G-protein coupled, 4". 

External links[edit]

  • "P2Y Receptors: P2Y4". IUPHAR Database of Receptors and Ion Channels. International Union of Basic and Clinical Pharmacology. 

Further reading[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.