P2RY4

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P2RY4
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases P2RY4, NRU, P2P, P2Y4, UNR, pyrimidinergic receptor P2Y4
External IDs MGI: 1926594 HomoloGene: 20568 GeneCards: P2RY4
Targeted by Drug
adenosine triphosphate, diquafosol, guanosine triphosphate, Inosine triphosphate, denufosol[1]
RNA expression pattern
PBB GE P2RY4 221466 at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_002565

NM_020621

RefSeq (protein)

NP_002556

NP_065646.1
NP_065646

Location (UCSC) Chr X: 70.26 – 70.26 Mb Chr X: 100.59 – 100.59 Mb
PubMed search [2] [3]
Wikidata
View/Edit Human View/Edit Mouse

P2Y purinoceptor 4 is a protein that in humans is encoded by the P2RY4 gene.[4][5]

The product of this gene, P2Y4, belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is responsive to uridine nucleotides, partially responsive to ATP, and not responsive to ADP.[5]

See also[edit]

References[edit]

  1. ^ "Drugs that physically interact with Pyrimidinergic receptor P2Y4 view/edit references on wikidata". 
  2. ^ "Human PubMed Reference:". 
  3. ^ "Mouse PubMed Reference:". 
  4. ^ Communi D, Pirotton S, Parmentier M, Boeynaems JM (Feb 1996). "Cloning and functional expression of a human uridine nucleotide receptor". J Biol Chem. 270 (52): 30849–52. doi:10.1074/jbc.270.52.30849. PMID 8537336. 
  5. ^ a b "Entrez Gene: P2RY4 pyrimidinergic receptor P2Y, G-protein coupled, 4". 

External links[edit]

  • "P2Y Receptors: P2Y4". IUPHAR Database of Receptors and Ion Channels. International Union of Basic and Clinical Pharmacology. 

Further reading[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.