P34 or P-34 may refer to:
- P34, a state first class road in Latvia - see List of National Roads in Latvia
- The protein encoded by the Cdk1 gene
- Tyrrell P34, a Formula One race car
- HMS Ultimatum (P34), a British Royal Navy Second World War submarine
- Wedell-Williams XP-34, a cancelled fighter project.
- P-34, pennant number of the ARA Santisima Trinidad (1948), an Argentine Navy frigate
- INS Ajay (P34), an Indian Navy corvette
- Papyrus 34, a manuscript of the Pauline epistles
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