PARP10

From Wikipedia, the free encyclopedia
Jump to: navigation, search
PARP10
Protein PARP10 PDB 2dhx.png
Available structures
PDB Human UniProt search: PDBe RCSB
Identifiers
Aliases PARP10, ARTD10, poly(ADP-ribose) polymerase family member 10
External IDs MGI: 3712326 HomoloGene: 53133 GeneCards: PARP10
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_032789
NM_001317895

NM_001163575
NM_001163576

RefSeq (protein)

NP_001304824
NP_116178

n/a

Location (UCSC) Chr 8: 143.98 – 144.01 Mb Chr 15: 76.23 – 76.24 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Poly [ADP-ribose] polymerase 10 is an enzyme that in humans is encoded by the PARP10 gene.[3][4]

Poly(ADP-ribose) polymerases (PARPs), such as PARP10, regulate gene transcription by altering chromatin organization by adding ADP-ribose to histones. PARPs can also function as transcriptional cofactors (Yu et al., 2005).[supplied by OMIM][4]

References[edit]

  1. ^ "Human PubMed Reference:". 
  2. ^ "Mouse PubMed Reference:". 
  3. ^ Ame JC, Spenlehauer C, de Murcia G (Jul 2004). "The PARP superfamily". BioEssays. 26 (8): 882–93. doi:10.1002/bies.20085. PMID 15273990. 
  4. ^ a b "Entrez Gene: PARP10 poly (ADP-ribose) polymerase family, member 10". 

Further reading[edit]