PCBP3

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PCBP3
Identifiers
Aliases PCBP3, ALPHA-CP3, poly(rC) binding protein 3
External IDs MGI: 1890470 HomoloGene: 23233 GeneCards: PCBP3
RNA expression pattern
PBB GE PCBP3 205663 at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_020528
NM_001130141

NM_021568
NM_001347216

RefSeq (protein)

NP_001334145
NP_067543

Location (UCSC) Chr 21: 45.64 – 45.94 Mb Chr 10: 76.76 – 76.96 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Poly(rC)-binding protein 3 is a protein that in humans is encoded by the PCBP3 gene.[3][4]

This gene encodes a member of the KH-domain protein subfamily. Proteins of this subfamily, also referred to as alpha-CPs, bind to RNA with a specificity for C-rich pyrimidine regions. Alpha-CPs play important roles in post-transcriptional activities and have different cellular distributions. This gene's protein is found in the cytoplasm, yet it lacks the nuclear localization signals found in other subfamily members. Multiple polyadenylation sites exist for this gene.[4]

References[edit]

  1. ^ "Human PubMed Reference:". 
  2. ^ "Mouse PubMed Reference:". 
  3. ^ Makeyev AV, Liebhaber SA (Sep 2000). "Identification of two novel mammalian genes establishes a subfamily of KH-domain RNA-binding proteins". Genomics. 67 (3): 301–16. PMID 10936052. doi:10.1006/geno.2000.6244. 
  4. ^ a b "Entrez Gene: PCBP3 poly(rC) binding protein 3". 

Further reading[edit]