PCDH18

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PCDH18
Identifiers
Aliases PCDH18, PCDH68L, protocadherin 18
External IDs MGI: 1920423 HomoloGene: 10389 GeneCards: PCDH18
RNA expression pattern
PBB GE PCDH18 gnf1h00321 at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001300828
NM_019035

NM_130448

RefSeq (protein)

NP_001287757
NP_061908

NP_569715.3
NP_569715

Location (UCSC) Chr 4: 137.52 – 137.53 Mb Chr 3: 49.74 – 49.76 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Protocadherin-18 is a protein that in humans is encoded by the PCDH18 gene.[3][4][5]

This gene belongs to the protocadherin gene family, a subfamily of the cadherin superfamily. This gene encodes a protein which contains 6 extracellular cadherin domains, a transmembrane domain and a cytoplasmic tail differing from those of the classical cadherins. Although its specific function is undetermined, the cadherin-related neuronal receptor is thought to play a role in the establishment and function of specific cell-cell connections in the brain.[5]

References[edit]

  1. ^ "Human PubMed Reference:". 
  2. ^ "Mouse PubMed Reference:". 
  3. ^ Nollet F, Kools P, van Roy F (Jul 2000). "Phylogenetic analysis of the cadherin superfamily allows identification of six major subfamilies besides several solitary members". J Mol Biol. 299 (3): 551–72. doi:10.1006/jmbi.2000.3777. PMID 10835267. 
  4. ^ Wolverton T, Lalande M (Sep 2001). "Identification and characterization of three members of a novel subclass of protocadherins". Genomics. 76 (1–3): 66–72. doi:10.1006/geno.2001.6592. PMID 11549318. 
  5. ^ a b "Entrez Gene: PCDH18 protocadherin 18". 

Further reading[edit]