PEX16

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PEX16
Identifiers
Aliases PEX16, PBD8A, PBD8B, peroxisomal biogenesis factor 16
External IDs MGI: 1338829 HomoloGene: 3537 GeneCards: 9409
RNA expression pattern
PBB GE PEX16 221603 at tn.png

PBB GE PEX16 221604 s at tn.png

PBB GE PEX16 49878 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_004813
NM_057174

NM_145122

RefSeq (protein)

NP_004804.1
NP_476515.1

NP_660104.2

Location (UCSC) Chr 11: 45.91 – 45.92 Mb Chr 2: 92.37 – 92.38 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Peroxisomal membrane protein PEX16 is a protein that in humans is encoded by the PEX16 gene.[3][4]

Function[edit]

The protein encoded by this gene is an integral peroxisomal membrane protein. An inactivating nonsense mutation localized to this gene was observed in a patient with Zellweger syndrome of the complementation group CGD/CG9. Expression of this gene product morphologically and biochemically restores the formation of new peroxisomes, suggesting a role in peroxisome organization and biogenesis. Alternative splicing has been observed for this gene and two variants have been described.[4]

Interactions[edit]

PEX16 has been shown to interact with PEX19.[5]

References[edit]

Further reading[edit]

External links[edit]