PEX3

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Peroxisomal biogenesis factor 3
Available structures
PDB Ortholog search: PDBe, RCSB
Identifiers
Symbols PEX3 ; PBD10A; TRG18
External IDs OMIM603164 MGI1929646 HomoloGene2691 GeneCards: PEX3 Gene
RNA expression pattern
PBB GE PEX3 203970 s at tn.png
PBB GE PEX3 203972 s at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 8504 56535
Ensembl ENSG00000034693 ENSMUSG00000019809
UniProt P56589 Q9QXY9
RefSeq (mRNA) NM_003630 NM_001164195
RefSeq (protein) NP_003621 NP_001157667
Location (UCSC) Chr 6:
143.45 – 143.49 Mb
Chr 10:
13.52 – 13.55 Mb
PubMed search [1] [2]

Peroxisomal biogenesis factor 3 is a protein that in humans is encoded by the PEX3 gene.[1][2]

Interactions[edit]

PEX3 has been shown to interact with PEX19.[3][4][5][6]

References[edit]

  1. ^ Kammerer S, Holzinger A, Welsch U, Roscher AA (Jun 1998). "Cloning and characterization of the gene encoding the human peroxisomal assembly protein Pex3p". FEBS Letters 429 (1): 53–60. doi:10.1016/S0014-5793(98)00557-2. PMID 9657383. 
  2. ^ "Entrez Gene: PEX3 peroxisomal biogenesis factor 3". 
  3. ^ Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, Berriz GF, Gibbons FD, Dreze M, Ayivi-Guedehoussou N, Klitgord N, Simon C, Boxem M, Milstein S, Rosenberg J, Goldberg DS, Zhang LV, Wong SL, Franklin G, Li S, Albala JS, Lim J, Fraughton C, Llamosas E, Cevik S, Bex C, Lamesch P, Sikorski RS, Vandenhaute J, Zoghbi HY, Smolyar A, Bosak S, Sequerra R, Doucette-Stamm L, Cusick ME, Hill DE, Roth FP, Vidal M (Oct 2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514. 
  4. ^ Mayerhofer PU, Kattenfeld T, Roscher AA, Muntau AC (Mar 2002). "Two splice variants of human PEX19 exhibit distinct functions in peroxisomal assembly". Biochemical and Biophysical Research Communications 291 (5): 1180–6. doi:10.1006/bbrc.2002.6568. PMID 11883941. 
  5. ^ Sacksteder KA, Jones JM, South ST, Li X, Liu Y, Gould SJ (Mar 2000). "PEX19 binds multiple peroxisomal membrane proteins, is predominantly cytoplasmic, and is required for peroxisome membrane synthesis". The Journal of Cell Biology 148 (5): 931–44. doi:10.1083/jcb.148.5.931. PMC 2174547. PMID 10704444. 
  6. ^ Fransen M, Wylin T, Brees C, Mannaerts GP, Van Veldhoven PP (Jul 2001). "Human pex19p binds peroxisomal integral membrane proteins at regions distinct from their sorting sequences". Molecular and Cellular Biology 21 (13): 4413–24. doi:10.1128/MCB.21.13.4413-4424.2001. PMC 87101. PMID 11390669. 

Further reading[edit]

External links[edit]