PEX6

From Wikipedia, the free encyclopedia
Jump to: navigation, search
PEX6
Identifiers
Aliases PEX6, PAF-2, PAF2, PBD4A, PDB4B, PXAAA1, HMLR2, peroxisomal biogenesis factor 6
External IDs MGI: 2385054 HomoloGene: 47914 GeneCards: 5190
RNA expression pattern
PBB GE PEX6 204545 at tn.png

PBB GE PEX6 320 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_000287
NM_001316313

NM_145488

RefSeq (protein)

NP_000278.3
NP_001303242.1

NP_663463.1

Location (UCSC) Chr 6: 42.96 – 42.98 Mb Chr 17: 46.71 – 46.73 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Peroxisome assembly factor 2 is a protein that in humans is encoded by the PEX6 gene.[3][4]

Interactions[edit]

PEX6 has been shown to interact with PEX1[5][6] and PEX26.[7]

References[edit]

  1. ^ "Human PubMed Reference:". 
  2. ^ "Mouse PubMed Reference:". 
  3. ^ Yahraus T, Braverman N, Dodt G, Kalish JE, Morrell JC, Moser HW, Valle D, Gould SJ (Aug 1996). "The peroxisome biogenesis disorder group 4 gene, PXAAA1, encodes a cytoplasmic ATPase required for stability of the PTS1 receptor". EMBO J. 15 (12): 2914–23. PMC 450231free to read. PMID 8670792. 
  4. ^ "Entrez Gene: PEX6 peroxisomal biogenesis factor 6". 
  5. ^ Tamura, S; Shimozawa N; Suzuki Y; Tsukamoto T; Osumi T; Fujiki Y (Apr 1998). "A cytoplasmic AAA family peroxin, Pex1p, interacts with Pex6p". Biochem. Biophys. Res. Commun. UNITED STATES. 245 (3): 883–6. doi:10.1006/bbrc.1998.8522. ISSN 0006-291X. PMID 9588209. 
  6. ^ Geisbrecht, B V; Collins C S; Reuber B E; Gould S J (Jul 1998). "Disruption of a PEX1-PEX6 interaction is the most common cause of the neurologic disorders Zellweger syndrome, neonatal adrenoleukodystrophy, and infantile Refsum disease". Proc. Natl. Acad. Sci. U.S.A. UNITED STATES. 95 (15): 8630–5. doi:10.1073/pnas.95.15.8630. ISSN 0027-8424. PMC 21127free to read. PMID 9671729. 
  7. ^ Matsumoto, Naomi; Tamura Shigehiko; Fujiki Yukio (May 2003). "The pathogenic peroxin Pex26p recruits the Pex1p-Pex6p AAA ATPase complexes to peroxisomes". Nat. Cell Biol. England. 5 (5): 454–60. doi:10.1038/ncb982. ISSN 1465-7392. PMID 12717447. 

Further reading[edit]

External links[edit]