From Wikipedia, the free encyclopedia
Jump to: navigation, search
Prohibitin 2
Symbols PHB2 ; BAP; BCAP37; Bap37; PNAS-141; REA; hBAP; p22
External IDs OMIM610704 MGI102520 HomoloGene5263 GeneCards: PHB2 Gene
Species Human Mouse
Entrez 11331 12034
Ensembl ENSG00000215021 ENSMUSG00000004264
UniProt Q99623 O35129
RefSeq (mRNA) NM_001144831 NM_007531
RefSeq (protein) NP_001138303 NP_031557
Location (UCSC) Chr 12:
6.97 – 6.97 Mb
Chr 6:
124.71 – 124.72 Mb
PubMed search [1] [2]

Prohibitin-2 is a protein that in humans is encoded by the PHB2 gene.[1][2][3]


PHB2 has been shown to interact with PTMA.[4]


  1. ^ Coates PJ, Nenutil R, McGregor A, Picksley SM, Crouch DH, Hall PA, Wright EG (Apr 2001). "Mammalian prohibitin proteins respond to mitochondrial stress and decrease during cellular senescence". Exp Cell Res 265 (2): 262–73. doi:10.1006/excr.2001.5166. PMID 11302691. 
  2. ^ Coates PJ, Jamieson DJ, Smart K, Prescott AR, Hall PA (Oct 1997). "The prohibitin family of mitochondrial proteins regulate replicative lifespan". Curr Biol 7 (8): 607–10. doi:10.1016/S0960-9822(06)00261-2. PMID 9259555. 
  3. ^ "Entrez Gene: PHB2 prohibitin 2". 
  4. ^ Martini, Paolo G V; Katzenellenbogen Benita S (Jun 2003). "Modulation of estrogen receptor activity by selective coregulators". J. Steroid Biochem. Mol. Biol. (England) 85 (2–5): 117–22. doi:10.1016/S0960-0760(03)00207-3. ISSN 0960-0760. PMID 12943695. 

Further reading[edit]