PICALM

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PICALM
Protein PICALM PDB 1hf8.png
Identifiers
Aliases PICALM, CALM, CLTH, LAP, phosphatidylinositol binding clathrin assembly protein
External IDs MGI: 2385902 HomoloGene: 111783 GeneCards: 8301
Genetically Related Diseases
Disease Name References
Alzheimer's disease
RNA expression pattern
PBB GE PICALM 212506 at tn.png

PBB GE PICALM 212511 at tn.png

PBB GE PICALM 215236 s at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001008660
NM_001206946
NM_001206947
NM_007166

RefSeq (protein)

NP_001008660.1
NP_001193875.1
NP_001193876.1
NP_009097.2
NP_001008660.1

Location (UCSC) Chr 11: 85.96 – 86.07 Mb Chr 7: 90.13 – 90.21 Mb
PubMed search [2] [3]
Wikidata
View/Edit Human View/Edit Mouse

Phosphatidylinositol binding clathrin assembly protein, also known as PICALM, is a protein which in humans is encoded by the PICALM gene.[1]


Interactions[edit]

PICALM has been shown to interact with CLTC.[2]

Clinical significance[edit]

In humans, certain alleles of this gene have been statistically associated with an increased risk of developing late-onset Alzheimer's disease.[3]

References[edit]

Further reading[edit]