PIGB

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PIGB
Identifiers
Aliases PIGB, GPI-MT-III, PIG-B, phosphatidylinositol glycan anchor biosynthesis class B
External IDs MGI: 1891825 HomoloGene: 3570 GeneCards: PIGB
Gene location (Human)
Chromosome 15 (human)
Chr. Chromosome 15 (human)[1]
Chromosome 15 (human)
Genomic location for PIGB
Genomic location for PIGB
Band 15q21.3 Start 55,318,960 bp[1]
End 55,355,648 bp[1]
RNA expression pattern
PBB GE PIGB 205452 at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_004855

NM_018889

RefSeq (protein)

NP_004846

NP_061377

Location (UCSC) Chr 15: 55.32 – 55.36 Mb Chr 9: 73.01 – 73.04 Mb
PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

GPI mannosyltransferase 3 is an enzyme that in humans is encoded by the PIGB gene.[5][6]

This gene encodes a transmembrane protein that is located in the endoplasmic reticulum and is involved in GPI-anchor biosynthesis. The glycosylphosphatidylinositol (GPI) anchor is a glycolipid found on many blood cells and serves to anchor proteins to the cell surface. This gene is thought to encode a member of a family of dolichol-phosphate-mannose (Dol-P-Man) dependent mannosyltransferases.[6]

References[edit]

Further reading[edit]