PLEKHO1

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PLEKHO1
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesPLEKHO1, CKIP-1, OC120, CKIP1, JBP, pleckstrin homology domain containing O1
External IDsMGI: 1914470 HomoloGene: 9448 GeneCards: PLEKHO1
Gene location (Human)
Chromosome 1 (human)
Chr.Chromosome 1 (human)[1]
Chromosome 1 (human)
Genomic location for PLEKHO1
Genomic location for PLEKHO1
Band1q21.2Start150,149,183 bp[1]
End150,164,720 bp[1]
RNA expression pattern
PBB GE PLEKHO1 218223 s at fs.png
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_016274
NM_001304722
NM_001304723
NM_001304724

NM_023320

RefSeq (protein)

NP_001291651
NP_001291652
NP_001291653
NP_057358

NP_075809

Location (UCSC)Chr 1: 150.15 – 150.16 MbChr 3: 95.99 – 96 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Pleckstrin homology domain-containing family O member 1 is a protein that in humans is encoded by the PLEKHO1 gene.[5][6]

Interactions[edit]

PLEKHO1 has been shown to interact with Casein kinase 2, alpha 1[5] and SMURF1.[7]

References[edit]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000023902 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000015745 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:".
  4. ^ "Mouse PubMed Reference:".
  5. ^ a b Bosc DG, Graham KC, Saulnier RB, Zhang C, Prober D, Gietz RD, Litchfield DW (Jun 2000). "Identification and characterization of CKIP-1, a novel pleckstrin homology domain-containing protein that interacts with protein kinase CK2". J Biol Chem. 275 (19): 14295–306. doi:10.1074/jbc.275.19.14295. PMID 10799509.
  6. ^ "Entrez Gene: PLEKHO1 pleckstrin homology domain containing, family O member 1".
  7. ^ Lu, Kefeng; Yin Xiushan; Weng Tujun; Xi Shenli; Li Li; Xing Guichun; Cheng Xuan; Yang Xiao; Zhang Lingqiang; He Fuchu (Aug 2008). "Targeting WW domains linker of HECT-type ubiquitin ligase Smurf1 for activation by CKIP-1". Nat. Cell Biol. England. 10 (8): 994–1002. doi:10.1038/ncb1760. PMID 18641638.

Further reading[edit]