PLRG1

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PLRG1
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases PLRG1, Cwc1, PRL1, PRP46, PRPF46, TANGO4, pleiotropic regulator 1
External IDs MGI: 1858197 HomoloGene: 2004 GeneCards: 5356
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_002669
NM_001201564

NM_016784

RefSeq (protein)

NP_001188493.1
NP_002660.1

NP_058064.2

Location (UCSC) Chr 4: 154.54 – 154.55 Mb Chr 3: 83.06 – 83.07 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Pleiotropic regulator 1 is a protein that in humans is encoded by the PLRG1 gene.[1]


Interactions[edit]

PLRG1 has been shown to interact with CDC5L.[2][3][4][5]

References[edit]

  1. ^ "Entrez Gene: PLRG1 pleiotropic regulator 1 (PRL1 homolog, Arabidopsis)". 
  2. ^ Ewing RM, Chu P, Elisma F, Li H, Taylor P, Climie S, McBroom-Cerajewski L, Robinson MD, O'Connor L, Li M, Taylor R, Dharsee M, Ho Y, Heilbut A, Moore L, Zhang S, Ornatsky O, Bukhman YV, Ethier M, Sheng Y, Vasilescu J, Abu-Farha M, Lambert JP, Duewel HS, Stewart II, Kuehl B, Hogue K, Colwill K, Gladwish K, Muskat B, Kinach R, Adams SL, Moran MF, Morin GB, Topaloglou T, Figeys D (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry". Mol. Syst. Biol. (England) 3 (1): 89. doi:10.1038/msb4100134. PMC 1847948. PMID 17353931. 
  3. ^ Ajuh P, Lamond AI (November 2003). "Identification of peptide inhibitors of pre-mRNA splicing derived from the essential interaction domains of CDC5L and PLRG1". Nucleic Acids Res. (England) 31 (21): 6104–16. doi:10.1093/nar/gkg817. PMC 275459. PMID 14576297. 
  4. ^ Ajuh P, Sleeman J, Chusainow J, Lamond AI (November 2001). "A direct interaction between the carboxyl-terminal region of CDC5L and the WD40 domain of PLRG1 is essential for pre-mRNA splicing". J. Biol. Chem. (United States) 276 (45): 42370–81. doi:10.1074/jbc.M105453200. ISSN 0021-9258. PMID 11544257. 
  5. ^ Ajuh P, Kuster B, Panov K, Zomerdijk JC, Mann M, Lamond AI (2000). "Functional analysis of the human CDC5L complex and identification of its components by mass spectrometry". EMBO J. 19 (23): 6569–81. doi:10.1093/emboj/19.23.6569. PMC 305846. PMID 11101529. 

Further reading[edit]