PMP2

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PMP2
Protein PMP2 PDB 1pmp.png
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesPMP2, FABP8, M-FABP, MP2, P2, peripheral myelin protein 2, Myelin P2 protein
External IDsMGI: 102667 HomoloGene: 20589 GeneCards: PMP2
Gene location (Human)
Chromosome 8 (human)
Chr.Chromosome 8 (human)[1]
Chromosome 8 (human)
Genomic location for PMP2
Genomic location for PMP2
Band8q21.13Start81,440,326 bp[1]
End81,447,523 bp[1]
RNA expression pattern
PBB GE PMP2 206826 at fs.png
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_002677
NM_001348381

NM_001030305

RefSeq (protein)

NP_002668
NP_001335310

NP_001025476

Location (UCSC)Chr 8: 81.44 – 81.45 MbChr 3: 10.18 – 10.18 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Myelin P2 protein is a protein that in humans is encoded by the PMP2 gene.[5][6][7] Myelin protein P2 is a constituent of peripheral nervous system (PNS) myelin, also present in small amounts in central nervous system (CNS) myelin. As a structural protein, P2 is thought to stabilize the myelin membranes, and may play a role in lipid transport in Schwann cells. Structurally, P2 belongs to the family of cytoplasmic fatty acid-binding proteins (FABPs).

References[edit]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000147588 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000052468 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:". 
  4. ^ "Mouse PubMed Reference:". 
  5. ^ Hayasaka K, Nanao K, Tahara M, Sato W, Takada G, Miura M, Uyemura K (Jan 1992). "Isolation and sequence determination of cDNA encoding P2 protein of human peripheral myelin". Biochem Biophys Res Commun. 181 (1): 204–7. doi:10.1016/S0006-291X(05)81402-0. PMID 1720307. 
  6. ^ Hayasaka K, Himoro M, Takada G, Takahashi E, Minoshima S, Shimizu N (Feb 1994). "Structure and localization of the gene encoding human peripheral myelin protein 2 (PMP2)". Genomics. 18 (2): 244–8. doi:10.1006/geno.1993.1462. PMID 8288226. 
  7. ^ "Entrez Gene: PMP2 peripheral myelin protein 2". 

Further reading[edit]