POLD2

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POLD2
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases POLD2, DNA polymerase delta 2, accessory subunit
External IDs MGI: 1097163 HomoloGene: 4538 GeneCards: POLD2
Gene location (Human)
Chromosome 7 (human)
Chr. Chromosome 7 (human)[1]
Chromosome 7 (human)
Genomic location for POLD2
Genomic location for POLD2
Band 7p13 Start 44,114,681 bp[1]
End 44,124,358 bp[1]
RNA expression pattern
PBB GE POLD2 201115 at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001127218
NM_001256879
NM_006230

NM_008894

RefSeq (protein)

NP_001120690
NP_001243808
NP_006221

NP_032920

Location (UCSC) Chr 7: 44.11 – 44.12 Mb Chr 7: 5.87 – 5.88 Mb
PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

DNA polymerase delta subunit 2 is an enzyme that in humans is encoded by the POLD2 gene.[5][6] It is a component of the DNA polymerase delta complex.


Interactions[edit]

POLD2 has been shown to interact with PCNA.[7]

References[edit]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000106628 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000020471 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:". 
  4. ^ "Mouse PubMed Reference:". 
  5. ^ Zhang J, Tan CK, McMullen B, Downey KM, So AG (Feb 1996). "Cloning of the cDNAs for the small subunits of bovine and human DNA polymerase delta and chromosomal location of the human gene (POLD2)". Genomics. 29 (1): 179–86. doi:10.1006/geno.1995.1229. PMID 8530069. 
  6. ^ "Entrez Gene: POLD2 polymerase (DNA directed), delta 2, regulatory subunit 50kDa". 
  7. ^ Lu, Xiaoqing; Tan Cheng-Keat; Zhou Jin-Qiu; You Min; Carastro L Michael; Downey Kathleen M; So Antero G (Jul 2002). "Direct interaction of proliferating cell nuclear antigen with the small subunit of DNA polymerase delta". J. Biol. Chem. United States. 277 (27): 24340–5. doi:10.1074/jbc.M200065200. ISSN 0021-9258. PMID 11986310. 

Further reading[edit]