PRND

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PRND
Protein PRND PDB 1lg4.png
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases PRND, DOPPEL, DPL, PrPLP, dJ1068H6.4, prion protein 2 (dublet), prion like protein doppel
External IDs MGI: 1346999 HomoloGene: 8236 GeneCards: PRND
Gene location (Human)
Chromosome 20 (human)
Chr. Chromosome 20 (human)[1]
Chromosome 20 (human)
Genomic location for PRND
Genomic location for PRND
Band 20p13 Start 4,721,910 bp[1]
End 4,728,460 bp[1]
RNA expression pattern
PBB GE PRND 222106 at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_012409

NM_001126338
NM_001278257
NM_001278520
NM_023043

RefSeq (protein)

NP_036541

NP_001119810
NP_001265186
NP_001265449
NP_075530

Location (UCSC) Chr 20: 4.72 – 4.73 Mb Chr 2: 131.95 – 131.96 Mb
PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Prion protein 2 (dublet), also known as PRND, or Doppel protein, is a protein which in humans is encoded by the PRND gene.[5]

Function[edit]

This gene is found on chromosome 20, approximately 20 kbp downstream of the gene encoding cellular prion protein, to which it is biochemically and structurally similar. The protein encoded by this gene is a membrane glycosylphosphatidylinositol-anchored glycoprotein that is found predominantly in testis. Mutations in this gene may lead to neurological disorders.[5]

References[edit]

Further reading[edit]