PRPF40A

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PRPF40A
Protein PRPF40A PDB 1uzc.png
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases PRPF40A, FBP-11, FBP11, FLAF1, FNBP3, HIP-10, HIP10, HYPA, NY-REN-6, Prp40, pre-mRNA processing factor 40 homolog A
External IDs MGI: 1860512 HomoloGene: 6377 GeneCards: PRPF40A
Gene location (Human)
Chromosome 2 (human)
Chr. Chromosome 2 (human)[1]
Chromosome 2 (human)
Genomic location for PRPF40A
Genomic location for PRPF40A
Band 2q23.3 Start 152,651,593 bp[1]
End 152,717,997 bp[1]
RNA expression pattern
PBB GE PRPF40A 218053 at fs.png

PBB GE PRPF40A 213729 at fs.png

PBB GE PRPF40A 214941 s at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_017892
NM_001354432
NM_001354431

NM_018785

RefSeq (protein)

NP_060362
NP_001341361
NP_001341360

NP_061255

Location (UCSC) Chr 2: 152.65 – 152.72 Mb Chr 2: 53.13 – 53.19 Mb
PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Pre-mRNA-processing factor 40 homolog A is a protein that in humans is encoded by the PRPF40A gene.[5][6][7]


Interactions[edit]

PRPF40A has been shown to interact with Huntingtin.[8]

References[edit]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000196504 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000061136 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:". 
  4. ^ "Mouse PubMed Reference:". 
  5. ^ Bedford MT, Reed R, Leder P (Sep 1998). "WW domain-mediated interactions reveal a spliceosome-associated protein that binds a third class of proline-rich motif: the proline glycine and methionine-rich motif". Proc Natl Acad Sci U S A. 95 (18): 10602–7. doi:10.1073/pnas.95.18.10602. PMC 27941Freely accessible. PMID 9724750. 
  6. ^ Wiesner S, Stier G, Sattler M, Macias MJ (Dec 2002). "Solution structure and ligand recognition of the WW domain pair of the yeast splicing factor Prp40". J Mol Biol. 324 (4): 807–22. doi:10.1016/S0022-2836(02)01145-2. PMID 12460579. 
  7. ^ "Entrez Gene: PRPF40A PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae)". 
  8. ^ Faber, P W; Barnes G T; Srinidhi J; Chen J; Gusella J F; MacDonald M E (Sep 1998). "Huntingtin interacts with a family of WW domain proteins". Hum. Mol. Genet. ENGLAND. 7 (9): 1463–74. doi:10.1093/hmg/7.9.1463. ISSN 0964-6906. PMID 9700202. 

Further reading[edit]