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Available structures
PDBOrtholog search: PDBe RCSB
AliasesCYTIP, B3-1, CASP, CYBR, CYTHIP, HE, PSCDBP, cytohesin 1 interacting protein
External IDsMGI: 2183535 HomoloGene: 3167 GeneCards: CYTIP
Gene location (Human)
Chromosome 2 (human)
Chr.Chromosome 2 (human)[1]
Chromosome 2 (human)
Genomic location for CYTIP
Genomic location for CYTIP
Band2q24.1Start157,414,619 bp[1]
End157,488,961 bp[1]
RNA expression pattern
PBB GE PSCDBP 209606 at fs.png
More reference expression data
RefSeq (mRNA)



RefSeq (protein)



Location (UCSC)Chr 2: 157.41 – 157.49 MbChr 2: 58.13 – 58.2 Mb
PubMed search[3][4]
View/Edit HumanView/Edit Mouse

Cytohesin-interacting protein is a protein that in humans is encoded by the CYTIP gene.[5][6][7][8]

The protein encoded by this gene contains 2 leucine zipper domains and a putative C-terminal nuclear targeting signal, and it does not have any hydrophobic regions. This protein is expressed weakly in resting NK and T cells.[8]


  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000115165 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000026832 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:". 
  4. ^ "Mouse PubMed Reference:". 
  5. ^ Dixon B, Sahely B, Liu L, Pohajdak B (Jan 1994). "Cloning a cDNA from human NK/T cells which codes for an unusual leucine zipper containing protein". Biochim Biophys Acta. 1216 (2): 321–4. doi:10.1016/0167-4781(93)90165-a. PMID 8241278. 
  6. ^ Kim HS (Jun 1999). "Assignment of the human B3-1 gene (PSCDBP) to chromosome 2 band q11.2 by radiation hybrid mapping". Cytogenet Cell Genet. 84 (1-2): 95. doi:10.1159/000015226. PMID 10343115. 
  7. ^ Tang P, Cheng TP, Agnello D, Wu CY, Hissong BD, Watford WT, Ahn HJ, Galon J, Moss J, Vaughan M, O'Shea JJ, Gadina M (Mar 2002). "Cybr, a cytokine-inducible protein that binds cytohesin-1 and regulates its activity". Proc Natl Acad Sci USA. 99 (5): 2625–9. doi:10.1073/pnas.052712999. PMC 122398Freely accessible. PMID 11867758. 
  8. ^ a b "Entrez Gene: PSCDBP pleckstrin homology, Sec7 and coiled-coil domains, binding protein". 

Further reading[edit]